In line with NIH’s strong support of the broad sharing of de-identified data generated from NIH-funded projects, NIH encourages the submission of data to dbGaP. Please ensure that any data submitted to dbGaP is compliant with NIH’s GWAS policy before submission and includes the following requirements for NIH-funded studies: Institutional certification – letter signed by the principal investigator and institutional official (VUMC IRB) confirming permission to submit to dbGaP Information about the study – title, description, history, inclusion and exclusion criteria, and a preview and certification of PI’s data Funding information To begin the submission process, the PI should contact their NIH Program Officer or Genomic Program Administrator. NIH publishes a flow-chart that illustrates and clarifies the submission process, as well as the different roles and responsibilities of both the PI and Program Officer/Genomic Program Administrator. If the study was not funded by the NIH, the PI should contact dbGaPemail@example.com for assistance.
Launched in response to the release of the GWAS policy, the Database of Genotypes and Phenotypes (dbGaP) is a NIH-sponsored repository designed to archive, curate, and distribute information produced by studies investigating the interaction of genotype and phenotype, in line with NIH’s strong support of the broad sharing of NIH-funded and -generated de-identified data. The database stores and offers access to those genetic and phenotypic datasets funded by NIH and other agencies, including the following information: Individual level molecular and phenotype data Analysis results Medical images General study information Research protocols and questionnaires dbGAP provides two levels of access: open and on-demand, which is available to anyone with no restrictions, and controlled-access, which requires preauthorization through application. Please note that the dbGaP controlled-access application process utilizes the SF 424 (R&R form) and requires a PI eRA Commons account. The application process for access to the controlled portion of dbGaP is as follows: The PI should first navigate to the controlled-access